Glutamine-driven mTORC1 activity enforces glycolytic bias, hyperactivation and aberrant proliferation in T cells in chronic B-cell leukemia
Nienke B. Goedhart, Elena Camerini, Gaspard Cretenet…·Helga Simon‐Molas
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Amsterdam UMC Location University of AmsterdamORCID 0000-0002-4916-2866Unclaimed ORCID profile · follow to get notified of new preprints
Mutual co-authors in cluster
7 papers
Recent·Most cited
Nienke B. Goedhart, Elena Camerini, Gaspard Cretenet…·Helga Simon‐Molas
Iuliia E. Karavaeva, Astrid Linde Basse, Samuel A.J. Trammell…·Zachary Gerhart‐Hines
This paper identifies SLC25A34 as a key regulator of interorganellar lipid cycling, integrating circadian rhythms, diet, and temperature to control thermogenic metabolism.
Madalena Vaz Santos, Bauke V. Schomakers, Marta Llobet Ayala…·Geert Hamer
This study characterizes the metabolome and proteome of human primordial germ cell-like cells to understand their metabolic changes and how they relate to development.
Bauke V. Schomakers, Adriana S Passadouro, Maria M. Trętowicz…·Signe Mosegaard
This study analyzes heart tissue from BTHS patients using integrated omics to identify metabolic and mitochondrial changes associated with the disease.
Jorge Sanz‐Ros, Javier Huete-Acevedo, Cristina Mas‐Bargues…·Consuelo Borrás
This study shows that young adipose-derived stem cell extracellular vesicles improve cardiac function and reduce aging-related damage in old mice.
Weisha Li, Bauke V. Schomakers, Michel van Weeghel…·Georges E. Janssens
The paper identifies plasma triacylglycerol (TG) length and saturation levels as markers of healthy aging in humans, showing that higher physical activity is linked to shorter TG chains and more double bonds.
Yasmine J. Liu, Georges E. Janssens, Rebecca L. McIntyre…·Riekelt H. Houtkooper
This study shows glycine supplementation extends C. elegans lifespan and alters gene expression, with effects dependent on the methionine cycle.