Glutamine-driven mTORC1 activity enforces glycolytic bias, hyperactivation and aberrant proliferation in T cells in chronic B-cell leukemia
Nienke B. Goedhart, Elena Camerini, Gaspard Cretenet…·Helga Simon‐Molas
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Amsterdam UMC Location University of AmsterdamORCID 0000-0002-0242-9113Unclaimed ORCID profile · follow to get notified of new preprints
Mutual co-authors in cluster
5 papers
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Nienke B. Goedhart, Elena Camerini, Gaspard Cretenet…·Helga Simon‐Molas
Madalena Vaz Santos, Bauke V. Schomakers, Marta Llobet Ayala…·Geert Hamer
This study characterizes the metabolome and proteome of human primordial germ cell-like cells to understand their metabolic changes and how they relate to development.
Bauke V. Schomakers, Adriana S Passadouro, Maria M. Trętowicz…·Signe Mosegaard
This study analyzes heart tissue from BTHS patients using integrated omics to identify metabolic and mitochondrial changes associated with the disease.
Weisha Li, Bauke V. Schomakers, Michel van Weeghel…·Georges E. Janssens
The paper identifies plasma triacylglycerol (TG) length and saturation levels as markers of healthy aging in humans, showing that higher physical activity is linked to shorter TG chains and more double bonds.
Rebecca L. McIntyre, Simone W. Denis, Rashmi Kamble…·Georges E. Janssens
The paper identifies atracurium as an FDA-approved compound that extends lifespan and healthspan in C. elegans by activating the FOXO/DAF-16 longevity pathway through neuromuscular acetylcholine receptor inhibition.