Ginger Geiger

Contemporary Victoria and Yamagata Influenza B Viruses Elicit Lineage-Specific Differences in Innate Immunity

This study compares innate immune responses to Victoria and Yamagata influenza B viruses, finding lineage-specific differences in immune kinetics, gene expression, and cellular tropism.

Passage of human-origin influenza A virus in swine tracheal epithelial cells selects for adaptive mutations in the hemagglutinin gene

This study shows that serial passage of a human-origin H3N2 virus in swine tracheal epithelial cells selects for adaptive HA mutations that increase viral fitness in swine cells.

Differential Cross-Protective Immunity is Elicited by Infection with Contemporary Influenza B Lineage Viruses

This study shows that contemporary Influenza B Victoria viruses provide cross-protection against Yamagata viruses, while Yamagata viruses do not offer similar protection, suggesting neuraminidase antibodies may be key to this asymmetry.