Passage of human-origin influenza A virus in swine tracheal epithelial cells selects for adaptive mutations in the hemagglutinin gene
Jong-Suk Mo, Lucas M. Ferreri, Ginger Geiger, Daniel Roberto Perez, Daniela S. Rajão
This study shows that serial passage of a human-origin H3N2 virus in swine tracheal epithelial cells selects for adaptive HA mutations that increase viral fitness in swine cells.
PLoS ONE · Aug 13, 2025Peer-reviewedMicrobiology