Author

Peter A. Dietzen

University of WashingtonORCID 0000-0002-4955-8713Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:comparative / phylogenetic analysis· 1 Approach:experimental assay· 1 Organism:human· 1 Organism:multiple species· 1 Research Focus:phylogenetics / evolution· 1

Frequent Co-Authors

Harmit Singh MalikiD· 2 shared Michael EmermaniD· 2 shared Caroline A. LangleyiD· 1 shared Jagdish Suresh PateliD· 1 shared Jeannette L. TenthoreyiD· 1 shared Laura GrafiD· 1 shared Luc America ChiiD· 1 shared Megan E. LevyiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersMicrobiology

Harmit Singh MalikORCID

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2 papers

Recent·Most cited

MicrobiologybioRxivPreprintOct 23, 2026

Targeted Engineering of Human MxA Yields a Broad-Spectrum Super-Restrictor of Human-Adapted Influenza Viruses

Megan E. Levy, Rechel Geiger, Luc America Chi…·Harmit Singh Malik

This study engineered hMxA to restrict multiple human-adapted influenza viruses as effectively as mMx1 by combining nuclear relocalization and specific amino acid changes.

DOI 10.64898/2026.10.22.760865

humanexperimental assay

Evolutionary BiologyProceedings of the National Academy of SciencesPeer-reviewedJan 24, 2025

Antiviral Mx proteins have an ancient origin and widespread distribution among eukaryotes

Caroline A. Langley, Peter A. Dietzen, Michael Emerman…·Harmit Singh Malik

The paper traces the evolutionary origins of Mx proteins, showing they predate the interferon system and are widespread across eukaryotes, including fungi, plants, and early-branching lineages.

14 citationstop 4%

multiple speciescomparative / phylogenetic analysis