Nicholas T. Woods

Integrative Proteomic Analysis Implicates Inhibition of Intracellular Protein Trafficking in Therapy-Induced Migrastasis in Prostate Cancer

This paper uses proteomic analysis to show that KBU2046 induces migrastasis in prostate cancer by inhibiting intracellular protein trafficking and altering signaling dynamics.

Proteome landscape of B-cell malignancies identifies mantle cell lymphoma protein signature

The paper identifies a proteomic signature of mantle cell lymphoma (MCL) using quantitative proteomics, revealing 10 upregulated proteins that may serve as therapeutic targets.

A Phosphoinositide Interacting Protein Coordinates Stress Precursor Activities

The paper shows Samd14 maintains autophagy balance in red blood cell precursors during acute anemia by interacting with PI3P and modulating VPS34 activity.

cAMP promotes acute lysosome biogenesis through TFEB nuclear import-export dynamics.

This study shows cAMP signaling regulates TFEB nuclear import and export, dynamically controlling lysosomal gene expression through PKA-dependent phosphorylation.