Author

Yin‐Shan Ng

Merck & Co., Inc., Rahway, NJ, USA (United States)ORCID 0000-0002-4982-1999Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Pathology· 2 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Patrìcia A. D'AmoreiD· 3 shared Zhengping HuiD· 3 shared Issahy CanoiD· 2 shared Anton LennikoviD· 1 shared Eleftherios I. PaschalisiD· 1 shared Emil KryukoviD· 1 shared Fengyang LeiiD· 1 shared Harper B. GordoniD· 1 shared

Activity by Year

2024-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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3 shared papersPathology

Patrìcia A. D'AmoreORCID

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3 papers

Recent·Most cited

Molecular BiologyAntioxidantsPeer-reviewedAug 14, 2025

Mechanism of PMC (2,2,5,7,8-pentamethyl-6-chromanol), a sterically hindered phenol antioxidant, in rescuing oxidized low-density lipoprotein-induced cytotoxicity in human retinal pigment epithelial cells

Suman Chaudhary, Jean Moon, Zhengping Hu…·Patrìcia A. D'Amore

This study investigates how PMC, a sterically hindered phenol antioxidant, protects human RPE cells from ox-LDL-induced damage by inhibiting Nrf2-mediated antioxidant response.

2 citations

humanexperimental assay

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PathologyCirculation ResearchPeer-reviewedNov 25, 2024

Deletion of the endothelial glycocalyx component endomucin leads to impaired glomerular structure and function

Zhengping Hu, Issahy Cano, Fengyang Lei…·Patrìcia A. D'Amore

This study shows that deleting endomucin in endothelial cells causes structural and functional issues in kidney glomeruli, including podocyte damage and albuminuria.

26 citationstop 2%

mouseproteomics

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PathologybioRxivPreprintJul 16, 2024

Endomucin knockout leads to delayed retinal vascular development and reduced ocular pathological neovascularization

Zhengping Hu, Issahy Cano, Anton Lennikov…·Patrìcia A. D'Amore

This study shows that Endomucin deficiency delays retinal vascular development and reduces pathological neovascularization in mouse models.

DOI 10.1101/2024.07.16.603729

mouseexperimental assay

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