Issahy Cano

This study identifies SIRT5 as a regulator of endothelial cell metabolism in the tumor microenvironment, showing its role in supporting breast cancer growth through vascular function.

This study shows that deleting endomucin in endothelial cells causes structural and functional issues in kidney glomeruli, including podocyte damage and albuminuria.

This study shows that Endomucin deficiency delays retinal vascular development and reduces pathological neovascularization in mouse models.