NeuroscienceJournal of NeuroinflammationPeer-reviewed
Inhibition of Endocannabinoid Degradation in Astrocytes Reprograms Glial Reactivity and Prevents Seizure Sequelae
Chudai Zeng, Fei Gao, Mei Hu…·Chu Chen
This study shows that inhibiting MAGL in astrocytes reduces seizures and neuroinflammation by activating CB1-PPAR-γ signaling, preserving synaptic function and preventing cognitive decline in epilepsy.
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