Author
The University of Texas at San Antonio Health Science CenterORCID 0000-0003-1287-8059Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Chudai Zeng, Fei Gao, Mei Hu…·Chu Chen
This study shows that inhibiting MAGL in astrocytes reduces seizures and neuroinflammation by activating CB1-PPAR-γ signaling, preserving synaptic function and preventing cognitive decline in epilepsy.
Li Sun, Mei Hu, Jianlu Lyu…·Chu Chen
This study identifies astrocytic monoacylglycerol lipase (MAGL) as a therapeutic target for Alzheimer's disease, showing that its inactivation reduces pathology and improves cognition in transgenic mice.
Dexiao Zhu, Jian Zhang, Xiaokuang Ma…·Chu Chen
The paper shows that inhibiting neuronal 2-AG metabolism impairs cognitive function in mice, while astrocytic inhibition can counterbalance these deficits.