Author

Madeline K. Loffredo

Boston UniversityORCID 0000-0002-5003-2081Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioengineering· 1 Synthetic Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:human· 1

Frequent Co-Authors

Brian S. GarrisoniD· 1 shared Carolyn A. HalleriD· 1 shared Elliot L. ChaikofiD· 1 shared Han Deng· 1 shared Hyun Ok HamiD· 1 shared Jingyao CheniD· 1 shared Juanjuan HuangiD· 1 shared Marcela Guzman Ayala· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperSynthetic Biology

Brian S. GarrisonORCID

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2 papers

Recent·Most cited

Synthetic BiologyiSciencePeer-reviewedAug 1, 2026

Tunable Universal OR-gated CAR T cells for AML

Md Nure Alom Siddiqui, Jingyao Chen, Juanjuan Huang…·Wilson W. Wong

This study develops a tunable OR-gated CAR system for AML treatment that effectively targets multiple antigens with reduced engineering complexity and minimized off-target toxicity.

3 citations

humanexperimental assay

𝕏 PostBluesky

BioengineeringbioRxivPreprintJul 10, 2026

Regio-selective sulfation of heparin mimicking polymers defines in vivo activity

Madeline K. Loffredo, Hyun Ok Ham, Maria Varghese…·Mark W. Grinstaff

This study develops and evaluates regioselectively sulfated polyamidosaccharides (disulPASs) as synthetic anticoagulants with activity similar to heparin.

DOI 10.64898/2026.07.09.737190

experimental assaydrug response / drug discovery

𝕏 PostBluesky