Author

Wenhua Kuang

Chinese Academy of SciencesORCID 0000-0002-5005-2330Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:benchmarking· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Approach:matrix factorization· 1 Approach:statistical model· 1

Frequent Co-Authors

Gan ZhangiD· 2 shared Zengqin DengiD· 2 shared Dan ZhouiD· 1 shared Fan Wu· 1 shared Haiyan ZhaoiD· 1 shared Haiyan ZhaoiD· 1 shared Hang LiuiD· 1 shared Huanyu Zhang· 1 shared

Activity by Year

2017-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersMicrobiology

Gan ZhangORCID

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3 papers

Recent·Most cited

MicrobiologyNucleic Acids ResearchPeer-reviewedDec 24, 2025

Structure and function of the nairovirus cap-snatching endonuclease

Wenhua Kuang, Zhenhua Tian, Gan Zhang…·Zengqin Deng

This study characterizes the structure and function of nairovirus cap-snatching endonucleases, revealing a unique two-metal-ion mechanism and identifying potent inhibitors.

7 citationstop 4%

experimental assay

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ImmunologybioRxivPreprintFeb 16, 2025

Neutralizing antibodies elicited by Nipah virus G-head nanoparticle target diverse sites and inhibit receptor binding and fusion

Dan Zhou, Yong Wang, Yanfeng Yao…·Haiyan Zhao

This study characterizes monoclonal antibodies against Nipah virus G-head nanoparticle, identifying neutralizing mechanisms and epitopes that could inform vaccine and therapeutic development.

DOI 10.1101/2025.02.16.638571

humanexperimental assay

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BioinformaticsNature CommunicationsPeer-reviewedSep 12, 2017

A Network Integration Approach for Drug-Target Interaction Prediction and Computational Drug Repositioning from Heterogeneous Information

Yunan Luo, Xinbin Zhao, Jingtian Zhou…·Jianyang Zeng

This paper introduces DTINet, a network integration method for predicting drug-target interactions and repositioning drugs, showing improved performance and validated novel COX inhibitor applications.

924 citationstop 1%

statistical modelmatrix factorization

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