Matthew J. Hangauer

The paper identifies FSP1 and histone deacetylases as suppressors of cancer persister cell ferroptosis and suggests combining GPX4 inhibitors with these targets to eliminate persister cells.

The paper identifies DFFB as a mechanism by which cancer persister cells suppress interferon to escape growth arrest and regrow after oncogene-targeted therapy.

The paper identifies antigenic cancer persister cells that survive direct T cell attack by leveraging apoptosis to avoid inflammatory death and acquiring mutations for immune resistance.