Anna E. Stuhlfire

FSP1 and histone deacetylases suppress cancer persister cell ferroptosis

The paper identifies FSP1 and histone deacetylases as suppressors of cancer persister cell ferroptosis and suggests combining GPX4 inhibitors with these targets to eliminate persister cells.

DFFB suppresses interferon to enable cancer persister cell regrowth

The paper identifies DFFB as a mechanism by which cancer persister cells suppress interferon to escape growth arrest and regrow after oncogene-targeted therapy.

Antigenic cancer persister cells survive direct T cell attack

The paper identifies antigenic cancer persister cells that survive direct T cell attack by leveraging apoptosis to avoid inflammatory death and acquiring mutations for immune resistance.