Author

Pauline Fahjen

Max Delbrück CenterORCID 0000-0002-5015-0643Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Research Focus:metabolism & bioenergetics· 1 Assay:metabolomics· 1 Organism:mouse· 1 Assay:proteomics· 1 Organism:rat· 1

Frequent Co-Authors

Frank EdelmanniD· 2 shared Gabriele G. SchiattarellaiD· 2 shared Philipp MertinsiD· 2 shared Alexandra M. Chitroceanu· 1 shared Alexandra Maria Chitroceanu· 1 shared Alina Frovola· 1 shared Alisa Uhrbach· 1 shared Annika WinkleriD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersPhysiology

Frank EdelmannORCID

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2 papers

Recent·Most cited

Myeloid cell recruitment propels right ventricular dysfunction in HFpEF via sterile inflammation.

Lara Jaeschke, Ceren Koçana, Alexandra Maria Chitroceanu, Annika Winkler, Hannah Kleitke, Pauline Fahjen, J. J. P. v. d. Kamp, David Faidel, Erik Asmus, Martin Meiser, Efstathios G. Stamatiades, Karolin W. Hublitz, Veronika Zach, Lucie Kretzler, Daniela Zurkan, , Jana Grune

This paper shows that myeloid cell recruitment drives right ventricular dysfunction in HFpEF through sterile inflammation in both mice and humans.

Circulation · Aug 18, 2026Peer-reviewedPhysiology

Butyrate Rescues Cardiac Metabolic Dysfunction in Hypertensive Heart Failure with Preserved Ejection Fraction

Sarah M. Kedziora, Sabrina Y. Geisberger, Oliver Popp, Alina Frovola, Alisa Uhrbach, Kristin Kräker, Nurana Tagiyeva, Marcus Kelm, Nikolaus Berndt, Yiming D. Zhang, Guido Mastrobuoni, Raquel Escrihuela-Branz, Theda U. P. Bartolomaeus, Lorenz Pixner, Pauline Fahjen, , Nadine Haase

This study shows that butyrate improves diastolic function and reduces fibrosis in hypertensive HFpEF rats by serving as an alternative energy source.

bioRxiv · Nov 28, 2025 · PreprintBiochemistry