Gabriele G. Schiattarella

This paper shows that myeloid cell recruitment drives right ventricular dysfunction in HFpEF through sterile inflammation in both mice and humans.

This study identifies IL-17A as a mediator of oxalate-induced cardiorenal injury in CKD, showing its role in inflammation and cardiac dysfunction.

This study identifies pulmonary microvascular rarefaction as a novel mechanism in heart failure, linking it to impaired gas exchange and worsened cardiac function.

This study uses fluorescence microscopy to show PERK remains mostly monomeric under ER stress, challenging the idea that oligomerization is required for its activation.

This study shows that butyrate improves diastolic function and reduces fibrosis in hypertensive HFpEF rats by serving as an alternative energy source.

The paper develops a cardiac spheroid model with monocytes to better mimic heart failure responses, showing improved functional and transcriptional changes compared to models without immune cells.

This study shows that inhibiting Runx1 protects against heart failure with preserved ejection fraction in mice by improving diastolic function and reducing hypertrophy and pulmonary edema.