Molecular BiologyMolecular Therapy — Nucleic AcidsPeer-reviewed
Development of conditional-siRNA programmable riboswitch for targeting adverse cardiac remodeling
Priyanka Gokulnath, Ane Miren Salvador, Caleb Graham…·Saumya Das
This paper develops a conditional-siRNA system that targets calcineurin in cardiac cells to reduce hypertrophy by responding to nppa mRNA, showing specific activation under stress conditions.
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