Author

Ane Miren Salvador

Harvard UniversityORCID 0000-0002-6008-0976Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetics· 1 Molecular Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:benchmarking· 1 Organism:human· 1 Organism:rat· 1 Approach:statistical model· 1

Frequent Co-Authors

Aidan R. O’BrieniD· 1 shared Amy Gonzales· 1 shared Andrew S. I. LoudoniD· 1 shared Andrew W. TraffordiD· 1 shared Anne N. HarringtoniD· 1 shared Antony D. AdamsoniD· 1 shared Anyonya R. GunturiD· 1 shared Atsushi YoshikiiD· 1 shared

Activity by Year

2019-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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1 shared paperGenetics

Aidan R. O’BrienORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

NeurosciencebioRxivPreprintAug 3, 2026

pH-dependent anti-TfR1 NANOBODY(R) molecules deliver efficacious oligonucleotide payloads to muscle and CNS tissues

Emily A Hoyt, Kristof Moonens, Chiara Rapisarda…·Nina C. Leksa

This study develops anti-TfR1 NANOBODY(R) molecules that deliver siRNA and ASO payloads to muscle and CNS tissues, achieving significant mRNA knockdown.

DOI 10.64898/2026.07.29.741483

mousehuman

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Molecular BiologyMolecular Therapy — Nucleic AcidsPeer-reviewedAug 5, 2025

Development of conditional-siRNA programmable riboswitch for targeting adverse cardiac remodeling

Priyanka Gokulnath, Ane Miren Salvador, Caleb Graham…·Saumya Das

This paper develops a conditional-siRNA system that targets calcineurin in cardiac cells to reduce hypertrophy by responding to nppa mRNA, showing specific activation under stress conditions.

1 citation

ratexperimental assay

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GeneticsGenome biologyPeer-reviewedAug 25, 2019

Re-Evaluating One-step Generation of Mice Carrying Conditional Alleles by CRISPR-Cas9-Mediated Genome Editing Technology

Channabasavaiah B. Gurumurthy, Aidan R. O’Brien, Rolen M. Quadros…·Atsushi Yoshiki

The paper re-evaluates the efficiency of a CRISPR-Cas9 method for generating conditional knockout alleles in mice, finding very low success rates and high rates of undesired alleles.

102 citationstop 3%

mousestatistical model

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