NeurosciencebioRxivPreprint
Astroglial deficiency for oligophrenin-1 contributes to intellectual disability
Noémie Cresto, Pascal Ezan, Laure‐Elise Pillet…·Nathalie Rouach
This study shows that astroglial Ophn1 deficiency impairs synaptic transmission and behavior, with potential therapeutic targeting of the RhoA/ROCK pathway.
DOI 10.1101/2025.01.09.632152