Condensate-Driven Triglyceride Depletion Links alpha-Synuclein to Mitochondrial Dysfunction
Tao Zhang, María Eugenia Goya, Alejandro Herrón-Bedoya…·Ellen A. A. Nollen
This study shows that alpha-synuclein condensation disrupts lipid metabolism, reduces triacylglycerols, and impairs mitochondrial function in C. elegans, with potential therapeutic implications for Parkinson's disease.