Tao Zhang

This study identifies a PPARγ-like signaling pathway in C. elegans that links lipid metabolism and mitochondrial quality control to maintain neuronal function.

This study shows that alpha-synuclein condensation disrupts lipid metabolism, reduces triacylglycerols, and impairs mitochondrial function in C. elegans, with potential therapeutic implications for Parkinson's disease.

This study shows that tumor-expressed nsGSLs impair OT-I T cell activation in vitro and promote tumor growth in vivo by evading immune responses.