Author
King Abdullah University of Science and TechnologyORCID 0000-0002-5058-9445Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Safia Aljedani, Anandsukeerthi Sandholu, Abdullah Aldehaiman…·Stefan T. Arold
This study identifies how SH3 domains activate PI3K by engaging in tertiary interactions with p85, revealing a mechanism for controlling activation through functional selection.
Giovanni Colombo, Israa Salem, Kacper Szczepski…·Stefan T. Arold
This study identifies a novel mechanism of phase separation driven by the Janus-class KFL region of PYK2, showing its role in kinase activation and cell adhesion.
Tanvir Alam, Meshari Alazmi, Rayan Naser…·Stefan T. Arold
The paper identifies LD motifs in the human proteome, reveals their role in cell adhesion and migration, and traces their evolutionary origin to a common ancestor.