Author

Adrien Lugari

Centre National de la Recherche ScientifiqueORCID 0000-0001-8337-6043Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:biophysical modeling· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:experimental assay· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

Abdullah AldehaimaniD· 1 shared Afaque A. MominiD· 1 shared Anandsukeerthi SandholuiD· 1 shared Haiyan WuiD· 1 shared John Edward LadburyiD· 1 shared Jonathan BackeriD· 1 shared Łukasz JaremkoiD· 1 shared Lydia W. T. CheungiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperBiochemistry

Abdullah AldehaimanORCID

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1 paper

Recent·Most cited

BiochemistryCommunications BiologyPeer-reviewedJan 19, 2026

Functional selection in SH3-mediated activation of the PI3 kinase

Safia Aljedani, Anandsukeerthi Sandholu, Abdullah Aldehaiman…·Stefan T. Arold

This study identifies how SH3 domains activate PI3K by engaging in tertiary interactions with p85, revealing a mechanism for controlling activation through functional selection.

2 citations

experimental assaybiophysical modeling

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