Author

Bradley R. Groveman

National Institutes of HealthORCID 0000-0002-5059-7672Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Cathryn L. HaighiD· 1 shared Francesca Salerno· 1 shared Judit KuniD· 1 shared Kathryn S. BeaucheminiD· 1 shared Katie WilliamsiD· 1 shared Lisa M. Francomacaro· 1 shared Patrick Robison· 1 shared Surachai SupattaponeiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 28 mutual co-author links

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1 shared paperCell Biology

Cathryn L. HaighORCID

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1 paper

Recent·Most cited

Oligosaccharyltransferase (OST) complex inhibition effectively treats rodent and human prions

Kathryn S. Beauchemin, Judit Kun, Bradley R. Groveman, Katie Williams, Francesca Salerno, Lisa M. Francomacaro, Patrick Robison, Cathryn L. Haigh, Surachai Supattapone

This paper identifies OST complex inhibition as a novel therapeutic approach that reduces prion protein surface expression and prevents prion amplification in both rodent and human prion models.

PLoS Pathogens · Jan 12, 2026Peer-reviewedCell Biology