Jeannette S. Messer

Extracellular HSPB1 protects intestinal epithelial cells against ethanol-activated ferroptosis

This study shows extracellular HSPB1 protects intestinal epithelial cells from ethanol-induced ferroptosis but can also contribute to inflammation in chronic alcohol conditions.

CFTR dysfunction in the intestinal epithelium is sufficient to promote pathogenic expansion of E. coli and enhanced barrier permeability in cystic fibrosis

This study shows that CFTR dysfunction in intestinal epithelial cells promotes E. coli expansion and increased intestinal permeability in cystic fibrosis.

A preliminary study of HMGB1 defense in Crohn's disease

This study examines HMGB1 defense in Crohn's disease, finding reduced surface-associated HMGB1 and intestinal barrier defects in active lesions.