Apollo Stacy

CFTR dysfunction in the intestinal epithelium is sufficient to promote pathogenic expansion of E. coli and enhanced barrier permeability in cystic fibrosis

This study shows that CFTR dysfunction in intestinal epithelial cells promotes E. coli expansion and increased intestinal permeability in cystic fibrosis.

Metabolic Strategies That Enable Oral Commensal Persistence in a Lower Airway Environment

This study identifies metabolic strategies enabling Neisseria mucosa persistence in the inflamed lower airway, highlighting nitrate respiration and antibiotic resistance as key factors.

Sulfide is a keystone metabolite for gut homeostasis and immunity

This study shows that sulfide is essential for gut microbial and immune homeostasis, with its depletion causing immune dysfunction and impaired vaccine response.