Author

Akeem Santos

Cleveland ClinicORCID 0009-0002-3507-1602Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Assay:proteomics· 1

Frequent Co-Authors

Mohammed DwidariD· 2 shared Philip P. AherniD· 2 shared Adeline M. HajjariD· 1 shared Alexander Maynard· 1 shared Anne-Marie C. OverstreetiD· 1 shared Apollo StacyiD· 1 shared Austin M Williams· 1 shared Brandon Bakos· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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2 shared papersCancer Biology

Mohammed DwidarORCID

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintSep 24, 2026

Metabolic engineering of Salmonella enterica for coupled kynurenine sensing and depletion enhances antitumor efficacy

Kontham Kulangara Varsha, Akeem Santos, Tingting Xiao…·Mohammed Dwidar

This paper engineers Salmonella enterica to sense and deplete kynurenine in tumors, enhancing antitumor immune responses and efficacy in mouse models.

DOI 10.64898/2026.09.23.753816

mouseexperimental assay

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MicrobiologybioRxivPreprintSep 19, 2026

CFTR dysfunction in the intestinal epithelium is sufficient to promote pathogenic expansion of E. coli and enhanced barrier permeability in cystic fibrosis

Philip P. Ahern, Naseer Sangwan, Apollo Stacy…·Adeline M. Hajjar

This study shows that CFTR dysfunction in intestinal epithelial cells promotes E. coli expansion and increased intestinal permeability in cystic fibrosis.

DOI 10.64898/2026.09.18.752678

mouseproteomics

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