Author

Yunus Kuijpers

Medizinische Hochschule HannoverORCID 0000-0002-5075-3970Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetic & Genomic Medicine· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Research Focus:GWAS / association mapping· 1 Assay:multiome· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Cheng‐Jian XuiD· 2 shared Leo A. B. JoosteniD· 2 shared Martin JaegeriD· 2 shared Mihai Gheorghe NeteaiD· 2 shared Yang LiiD· 2 shared Aline de NooijeriD· 1 shared Bowen ZhangiD· 1 shared Frank L. van de VeerdonkiD· 1 shared

Activity by Year

2021-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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2 shared papersGenetic & Genomic Medicine

Cheng‐Jian XuORCID

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2 papers

Recent·Most cited

The genetic risk for COVID-19 severity is associated with defective innate immune responses

Yunus Kuijpers, Xiaojing Chu, Martin Jaeger, Simone J.C.F.M. Moorlag, Valerie A. C. M. Koeken, Bowen Zhang, Aline de Nooijer, Inge Grondman, Manoj Kumar Gupta, Nico A. F. Janssen, Vera P. Mourits, L. Charlotte J. de Bree, Quirijn de Mast, Frank L. van de Veerdonk, Leo A. B. Joosten, , Cheng‐Jian Xu

This study explores the physiological significance of genetic variants associated with COVID-19 severity using clinical, immunological, and multi-omics data from large cohorts, identifying pathways for prevention and therapy.

Frontiers in Immunology · May 12, 2022Peer-reviewedGenetic & Genomic Medicine

Evolution of cytokine production capacity in ancient and modern European populations

Jorge Domínguez‐Andrés, Yunus Kuijpers, Olivier B. Bakker, Martin Jaeger, Cheng‐Jian Xu, Jos W. M. van der Meer, Mattias Jakobsson, Jaume Bertranpetit, Leo A. B. Joosten, Yang Li, Mihai Gheorghe Netea

This study examines how immune-related traits evolved in ancient and modern European populations, finding that the Neolithic transition influenced cytokine production and disease susceptibility.

eLife · Sep 6, 2021Peer-reviewedGenomics