Maritere Urióstegui-Arcos

The paper identifies a spatial coordination between mRNA initiation and termination sites, proposing a 'Positional Initiation-Termination Axis' that influences isoform diversity.

The paper shows that transcription inhibition in cancer cells leads to the generation of DoGs, suggesting they are part of a cellular stress response.

The paper identifies EMATS genes and demonstrates their therapeutic potential by using small molecules and ASOs to enhance gene expression through splicing-dependent transcriptional activation.

The paper identifies a regulatory circuit involving LEC2, ABI3, and HSI/VAL proteins that controls ABI4 gene expression through RY cis-acting motifs and chromatin structure in plants.

The paper shows that disrupting TFIIH activities with TPL or THZ1 increases cancer cell sensitivity and identifies potential new cancer targets.