Yuhui Song

Lymphotoxin-driven cancer cell eradication by tumoricidal CD8+ tumor-infiltrating lymphocytes

This study identifies a novel CD8+ TIL subset that uses lymphotoxin and IFN pathways to kill cancer cells, linking LTB expression to clinical response in melanoma.

Immune-parenchymal multicellular niches are shared across distinct thyroid autoimmune diseases

The paper generates a multi-modal atlas of thyroid and blood cells from HT, GD, and controls, revealing shared immune niches despite distinct disease mechanisms.

Intraductal Papillary Mucinous Neoplasm Cellular Plasticity is linked with Repeat Element Dysregulation

This study uses spatial transcriptomics to show that IPMN subtypes form a molecular continuum originating from gastric-type cells, with repeat element expression linked to disease progression.