Author

Sua Ryu

Washington University in St. LouisORCID 0000-0002-5098-4963Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Jason D. WeberiD· 3 shared Kyle A. CottrelliD· 3 shared Jackson R. PierceiD· 2 shared Luisangely Soto TorresiD· 2 shared Addison A. Young· 1 shared Alex MabryiD· 1 shared Angela M. SchabiD· 1 shared Brenda BassiD· 1 shared

Activity by Year

2024-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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3 shared papersMolecular Biology

Jason D. WeberORCID

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Author profile →

3 papers

Recent·Most cited

ADAR1 Regulates Lipid Remodeling to Dictate Ferroptosis Sensitivity

Che-Pei Kung, Nick Terzich, Ma Xenia G. Ilagan, Michael J. Prinsen, Madhurima Kaushal, Raleigh D. Kladney, J. Weber, Alex Mabry, Luisangely Soto Torres, Emily R. Bramel, Eric C. Freeman, Thwisha Sabloak, Sua Ryu, William M. Weber, Kyle A. Cottrell, , Jason D. Weber

This study shows ADAR1 protects TNBC cells from ferroptosis by regulating lipid composition, and identifies cobimetinib as a potential therapeutic agent when combined with ADAR1 loss.

bioRxiv · Jan 16, 2025 · PreprintCancer Biology

Activation of PKR by a short-hairpin RNA

Kyle A. Cottrell, Sua Ryu, Helen Donelick, Hung Mai, Addison A. Young, Jackson R. Pierce, Brenda Bass, Jason D. Weber

This study shows that an shRNA targeting DDX54 can activate PKR through a dsRNA-mediated mechanism, highlighting the need for careful validation of gene function.

Scientific Reports · Oct 9, 2024Peer-reviewedMolecular Biology

Induction of viral mimicry upon loss of DHX9 and ADAR1 in breast cancer cells

Kyle A. Cottrell, Sua Ryu, Jackson R. Pierce, Luisangely Soto Torres, Holly E. Bohlin, Angela M. Schab, Jason D. Weber

The paper shows that loss of DHX9 and ADAR1 in breast cancer cells activates dsRNA sensing pathways, leading to a viral mimicry phenotype.

Cancer Research Communications · Mar 26, 2024Peer-reviewedMolecular Biology