Author

Jay X. J. Luo

Brigham and Women's HospitalORCID 0000-0002-5111-0192Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:gene regulatory network inference· 2 Organism:human· 2 Assay:ChIP-seq· 1 Approach:machine learning (classical)· 1 Organism:mouse· 1 Assay:scRNA-seq· 1 Approach:statistical model· 1

Frequent Co-Authors

Annika K K WeimeriD· 1 shared Anshul Bharat KundajeiD· 1 shared Belle A. MoyersiD· 1 shared Brian J. WaingeriD· 1 shared Chayse Arnhold· 1 shared Difei Zhu· 1 shared Dustin S. GriesemeriD· 1 shared E. Christopher Partridge· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperGenomics

Annika K K WeimerORCID

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2 papers

Recent·Most cited

Multi-omic profiling of human and mouse dorsal root ganglia enables targeted gene delivery to nociceptors

Lily S He, Parth Bhatia, Shamsuddin A. Bhuiyan, Evangelia Semizoglou, J. Wang, Jia Li, Joohyun Nam, Jay X. J. Luo, Chayse Arnhold, Difei Zhu, Mengyi Xu, Dustin S. Griesemer, Hyo Jeong Yong, Lorna Jayne, Evangeline Gilmer, , NIH PRECISION Human Pain Network

The paper identifies cis-regulatory elements for targeted gene delivery to nociceptors using multi-omic profiling and develops a sequence-based model to design synthetic enhancers.

bioRxiv · Mar 12, 2026 · PreprintNeuroscience

Comparative atlas of genome-wide chromatin-associated protein co-occupancy

Shannon M. White, Belle A. Moyers, Tao Wang, Mark Mackiewicz, Annika K K Weimer, Fabian Grubert, Vivekanandan Ramalingam, Jay X. J. Luo, Lixia Jiang, Minyi Shi, Xinqiong Yang, Tristan Chou, Jie Zhai, Konor von Kraut, Jessika Adrian, , Michael P. Snyder

The paper identifies cell type-specific and shared chromatin-associated protein co-association modules using ChIP-Seq and machine learning in K562 and HepG2 cells.

bioRxiv · Dec 17, 2024 · PreprintGenomics