Author

Difei Zhu

Brigham and Women's Hospital

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:scRNA-seq· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:mouse· 1

Frequent Co-Authors

Dustin S. GriesemeriD· 2 shared Evangelia SemizoglouiD· 2 shared Lite YangiD· 2 shared NIH PRECISION Human Pain Network· 2 shared Parth BhatiaiD· 2 shared Selwyn S. JayakariD· 2 shared Shamsuddin A. BhuiyaniD· 2 shared William R. RenthaliD· 2 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersNeuroscience

Dustin S. GriesemerORCID

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Author profile →

2 papers

Recent·Most cited

Multi-omic profiling of human and mouse dorsal root ganglia enables targeted gene delivery to nociceptors

Lily S He, Parth Bhatia, Shamsuddin A. Bhuiyan, Evangelia Semizoglou, J. Wang, Jia Li, Joohyun Nam, Jay X. J. Luo, Chayse Arnhold, Difei Zhu, Mengyi Xu, Dustin S. Griesemer, Hyo Jeong Yong, Lorna Jayne, Evangeline Gilmer, , NIH PRECISION Human Pain Network

The paper identifies cis-regulatory elements for targeted gene delivery to nociceptors using multi-omic profiling and develops a sequence-based model to design synthetic enhancers.

bioRxiv · Mar 12, 2026 · PreprintNeuroscience

A Reference Atlas of the Human Dorsal Root Ganglion

Shamsuddin A. Bhuiyan, Saad S. Nagi, Ishwarya Sankaranarayanan, Evangelia Semizoglou, Dmitry Usoskin, Lite Yang, Huasheng Yu, Asta Arendt-Tranholm, Zachariah Bertels, Parth Bhatia, Otmane Bouchatta, Kevin Boyer, Anna M. Cervantes, Joshua I. Chalif, Himanshu Chintalapudi, , NIH PRECISION Human Pain Network

This paper constructs a human dorsal root ganglion reference atlas, identifying 22 neuronal subtypes and 10 non-neuronal cell types, and reveals functional differences between human and mouse DRG neurons.

bioRxiv · Nov 5, 2025 · PreprintNeuroscience