Author
Brigham and Women's HospitalORCID 0000-0001-9753-6124Unclaimed ORCID profile · follow to get notified of new preprints
6 papers
Recent·Most cited
Lily S He, Parth Bhatia, Shamsuddin A. Bhuiyan…·NIH PRECISION Human Pain Network
The paper identifies cis-regulatory elements for targeted gene delivery to nociceptors using multi-omic profiling and develops a sequence-based model to design synthetic enhancers.
Shamsuddin A. Bhuiyan, Saad S. Nagi, Ishwarya Sankaranarayanan…·NIH PRECISION Human Pain Network
This paper constructs a human dorsal root ganglion reference atlas, identifying 22 neuronal subtypes and 10 non-neuronal cell types, and reveals functional differences between human and mouse DRG neurons.
Shamsuddin A. Bhuiyan, Mengyi Xu, Lite Yang…·William R. Renthal
The paper builds harmonized cross-species cell atlases of DRG and TG, identifies 29 cell types across 6 species, and shows transcriptomic similarities and differences in sensory neurons.
Evangelia Semizoglou, Laure Lo Re, Steven J. Middleton…·Kim I. Chisholm
This study uses in vivo calcium imaging to characterize the stimulus-response function of mouse C-low threshold mechanoreceptors to mechanical stimuli.
Evangelia Semizoglou, Clive Gentry, Nisha Vastani…·Stuart Bevan
This study shows TRPA1 inhibition enhances KOR activity in sensory neurons, leading to analgesia, and identifies TRP channel regulation of GPCR activity as a novel mechanism for peripherally mediated pain relief.