Author

Hyo Jeong Yong

Brigham and Women's HospitalORCID 0000-0002-9172-3233Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

William R. RenthaliD· 2 shared Aakanksha JainiD· 1 shared Anu Shahapal· 1 shared Arfaxad Reyes‐AlcaraziD· 1 shared Biyao ZhangiD· 1 shared Brian J. WaingeriD· 1 shared Caleb Hu· 1 shared Chayse Arnhold· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersNeuroscience

William R. RenthalORCID

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3 papers

Recent·Most cited

Multi-omic profiling of human and mouse dorsal root ganglia enables targeted gene delivery to nociceptors

Lily S He, Parth Bhatia, Shamsuddin A. Bhuiyan, Evangelia Semizoglou, J. Wang, Jia Li, Joohyun Nam, Jay X. J. Luo, Chayse Arnhold, Difei Zhu, Mengyi Xu, Dustin S. Griesemer, Hyo Jeong Yong, Lorna Jayne, Evangeline Gilmer, , NIH PRECISION Human Pain Network

The paper identifies cis-regulatory elements for targeted gene delivery to nociceptors using multi-omic profiling and develops a sequence-based model to design synthetic enhancers.

bioRxiv · Mar 12, 2026 · PreprintNeuroscience

Lipid nanoparticle delivery of siRNA to dorsal root ganglion neurons to treat pain

Xiangfei Han, Veselina Petrova, Yudong Song, Yu‐Ting Cheng, Xingya Jiang, Hui Hua Zhou, Caleb Hu, Dean Shuailin Chen, Hyo Jeong Yong, Hyoung Woo Kim, Biyao Zhang, Omer Barkai, Aakanksha Jain, William R. Renthal, Philipp B. Lirk, , Jinjun Shi

This study demonstrates the use of lipid nanoparticles to deliver siRNA to dorsal root ganglion neurons, effectively silencing TRPV1 and reducing pain-related behaviors.

bioRxiv · Jan 23, 2025 · PreprintNeuroscience

Is FAM19A5 an adipokine? Peripheral FAM19A5 in wild-type, FAM19A5 knock-out, and LacZ knock-in mice.

Hoyun Kwak, Eun-Ho Cho, Eun Bee Cho, Yoo-Na Lee, Anu Shahapal, Hyo Jeong Yong, Arfaxad Reyes‐Alcaraz, Yongwoo Jeong, Yerim Lee, Minhyeok Lee, Nui Ha, Sitaek Oh, Jae Keun Lee, Won Suk Lee, Won Kyum Kim, , Jae Young Seong

This study examines FAM19A5 expression and function in mice, finding low peripheral levels and no significant interaction with S1PR2.

Molecules and Cells · Oct 18, 2024Peer-reviewedGenetics