ImmunologyTheranosticsPeer-reviewed
Imaging CRISPR-Edited CAR-T Cell Therapies with Optical and Positron Emission Tomography Reporters
Rafael E. Sanchez‐Pupo, John Joseph Kelly, Nourhan Shalaby…·John Andrew Ronald
This paper develops tRACE-CAR T cells with optical and PET imaging reporters to track CAR-T cell distribution and activity in vivo, showing improved tracking and therapeutic effectiveness.