Author

Rafael E. Sanchez‐Pupo

Western UniversityORCID 0000-0002-6970-2137Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1 Assay:imaging· 1

Frequent Co-Authors

John Andrew RonaldiD· 2 shared John Joseph KellyiD· 2 shared Andrew M. DeweyertiD· 1 shared Brooke O'Donnell· 1 shared Carlijn Van Kessel· 1 shared Carolina Herrera· 1 shared Danielle E. JohnstoniD· 1 shared Francisco Martínez‐Santiesteban· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersCancer Biology

John Andrew RonaldORCID

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2 papers

Recent·Most cited

Pannexin 1 inhibition reduces tumorigenic properties of patient-derived glioblastoma cells through the HIPPO and Wnt signalling pathways

Danielle E. Johnston, Matthew S. Huver, Rehanna Kanji, Carlijn Van Kessel, John Joseph Kelly, Rafael E. Sanchez‐Pupo, Brooke O'Donnell, Norah Defamie, Rebecca Lau, Carolina Herrera, Andrew M. Deweyert, Marc Mesnil, John Andrew Ronald, Matthew O. Hebb, Silvia Peñuela

bioRxiv · Sep 7, 2026 · PreprintCancer Biology

Imaging CRISPR-Edited CAR-T Cell Therapies with Optical and Positron Emission Tomography Reporters

Rafael E. Sanchez‐Pupo, John Joseph Kelly, Nourhan Shalaby, Ying Xia, Francisco Martínez‐Santiesteban, Jasmine Lau, Ivy E. Verriet, Matthew S. Fox, Justin W. Hicks, Jonathan Dale Thiessen, John Andrew Ronald

This paper develops tRACE-CAR T cells with optical and PET imaging reporters to track CAR-T cell distribution and activity in vivo, showing improved tracking and therapeutic effectiveness.

Theranostics · Jan 1, 2026Peer-reviewedImmunology