Author
Amgen (United States)ORCID 0000-0002-5125-6511Unclaimed ORCID profile · follow to get notified of new preprints
4 papers
Recent·Most cited
Joyce Ka Yu Tse, Xuan Liu, Ittai E. Eres…·Chi-Ming Li
The paper identifies bZIP transcription factors as key regulators of IL-2-induced Treg activation, linking chromatin accessibility changes to Th1/Th2 molecular phenotypes and metabolic pathways.
Richard Gill, Daniel Lu, Ittai E. Eres…·Yi‐Hsiang Hsu
The paper identifies causal genes in heart disease GWAS loci by integrating Hi-C, chromatin accessibility, and transcriptomic data, revealing regulatory relationships in cardiac fibroblasts.
Jiamiao Lu, Elissa Swearingen, Miki Hardy…·Michael M. Ollmann
The paper identifies RAB18 as a key regulator that enhances GalNAc-conjugated siRNA efficacy in Hep3B cells by improving siRNA delivery and RISC access.
Jiamiao Lu, Patrick J. Collins, Ki Jeong Lee…·Songli Wang
This study develops and tests a tBID-based safety switch system for engineered T cells to manage toxicity and persistence, showing up to 90% cell elimination in vitro.