Author

Patrick J. Collins

Amgen (United States)ORCID 0000-0002-7141-7503Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Approach:statistical model· 1

Frequent Co-Authors

Chi-Ming LiiD· 2 shared Jiamiao LuiD· 2 shared Songli WangiD· 2 shared Bin WuiD· 1 shared Daniel LuiD· 1 shared Elissa Swearingen· 1 shared Eric Yuan· 1 shared Ki Jeong LeeiD· 1 shared

Activity by Year

2021-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersMolecular Biology

Chi-Ming LiORCID

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2 papers

Recent·Most cited

Molecular BiologyMolecular Therapy — Nucleic AcidsPeer-reviewedApr 2, 2022

RAB18 is a key regulator of GalNAc conjugated siRNA induced silencing in Hep3B cells

Jiamiao Lu, Elissa Swearingen, Miki Hardy…·Michael M. Ollmann

The paper identifies RAB18 as a key regulator that enhances GalNAc-conjugated siRNA efficacy in Hep3B cells by improving siRNA delivery and RISC access.

8 citations

humanbulk RNA-seq

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Molecular BiologyAnnals of Translational MedicinePeer-reviewedNov 1, 2021

In vitro assessment of an engineered tBID-based safety switch system in human T lymphocytes

Jiamiao Lu, Patrick J. Collins, Ki Jeong Lee…·Songli Wang

This study develops and tests a tBID-based safety switch system for engineered T cells to manage toxicity and persistence, showing up to 90% cell elimination in vitro.

DOI 10.21037/atm-21-443

humanbulk RNA-seq

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