Author

Schelto Kruijff

University Medical Center GroningenORCID 0000-0002-5151-7320Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Abel Soto-GameziD· 2 shared Anne L. Jellema-de BruiniD· 2 shared Gabriella De VitaiD· 2 shared Robert Paul CoppesiD· 2 shared Rufina MaturiiD· 2 shared Davide CinatiD· 1 shared Matteo EspositoiD· 1 shared Mirjam BaanstraiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

8 top collaborators · 26 mutual co-author links

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2 shared papersCell Biology

Abel Soto-GamezORCID

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2 papers

Recent·Most cited

Role of Klhl14 in senescence and epithelial-to-mesenchymal transition via TGF- modulation

Rufina Maturi, Abel Soto-Gamez, Anne L. Jellema-de Bruin, Mirjam Baanstra, Matteo Esposito, Schelto Kruijff, Gabriella De Vita, Robert Paul Coppes

This study identifies KLHL14's role in maintaining thyroid epithelial identity and regulating tissue homeostasis by modulating TGF-β signaling, with implications for thyroid cancer.

Cell Death and Disease · Jun 30, 2026Peer-reviewedCell Biology

Radiation-induced interferon-I response impairs thyroid organoid function

Rufina Maturi, Davide Cinat, Anne L. Jellema-de Bruin, Gabriella De Vita, Schelto Kruijff, Robert Paul Coppes, Abel Soto-Gamez

This study identifies IFN-β signaling as a key mediator of radiation-induced inflammation and cell death in thyroid organoids, with dual effects on survival and regenerative potential.

Radiotherapy and Oncology · Feb 21, 2026Peer-reviewedCell Biology