Author
University Medical Center GroningenORCID 0009-0006-0493-3651Unclaimed ORCID profile · follow to get notified of new preprints
5 papers
Recent·Most cited
Rufina Maturi, Abel Soto-Gamez, Anne L. Jellema-de Bruin…·Robert Paul Coppes
This study identifies KLHL14's role in maintaining thyroid epithelial identity and regulating tissue homeostasis by modulating TGF-β signaling, with implications for thyroid cancer.
Rufina Maturi, Davide Cinat, Anne L. Jellema-de Bruin…·Abel Soto-Gamez
This study identifies IFN-β signaling as a key mediator of radiation-induced inflammation and cell death in thyroid organoids, with dual effects on survival and regenerative potential.
Davide Cinat, Ryan van der Wal, Mirjam Baanstra…·Robert Paul Coppes
The paper shows that transposable element derepression triggers IFN-I signaling, boosting stem/progenitor cell activity after irradiation.
Davide Cinat, Rufina Maturi, Jeremy P Gunawan…·Robert Paul Coppes
The paper identifies Notch signaling as essential for maintaining stem/progenitor cell self-renewal and migration post-irradiation in salivary and other gland organoids.
Luc H. J. Sondorp, Eline C. Jager, Ines Farinha Antunes…·Schelto Kruijff
This paper establishes a patient-derived MTC organoid model for drug screening and PET tracer uptake analysis, showing successful culture and functional resemblance to native tissue.