NeuroscienceBrain ResearchPeer-reviewed
Antagonism of kappa opioid receptors accelerates the development of L-DOPA-induced dyskinesia in a preclinical model of moderate dopamine depletion
Andrew J. Flores, Mitchell J. Bartlett, Blake T. Seaton…·Torsten Falk
This study shows that blocking kappa opioid receptors increases the rate of L-DOPA-induced dyskinesia development in a rat Parkinson's model but does not affect motor symptoms or tonic dopamine levels.
4 citations