Author

Michael L. Heien

University of ArizonaORCID 0000-0001-5164-9596Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Organism:rat· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Mitchell J. BartlettiD· 3 shared Torsten FalkiD· 3 shared Andrew J. FloresiD· 1 shared Blake T. SeatoniD· 1 shared Brian M. CoxiD· 1 shared Chidiebere Ogbu· 1 shared Daniel F. HilliD· 1 shared Dong Lu· 1 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

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3 shared papersNeuroscience

Mitchell J. BartlettORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Early intervention with a PACAP lactoside following repetitive mild traumatic brain injury prevents persistent LHb hyperactivity and motivational deficits in male mice

Emily H. Thomas, Troy E. Smith, Lajos Z. Szabò, William J. Flerlage, Fahad Al‐Obeidi, Oana L. Rujan, Shawn Gouty, Regina C. Armstrong, Brian M. Cox, Torsten Falk, Michael L. Heien, Chidiebere Ogbu, Minying Cai, Mitchell J. Bartlett, Robin L. Polt, Fereshteh S. Nugent

This study shows that early administration of a PACAP agonist prevents mTBI-induced LHb hyperactivity and motivational deficits in mice, while late administration has limited efficacy and potential side effects.

bioRxiv · Sep 1, 2026 · PreprintNeuroscience

Antagonism of kappa opioid receptors accelerates the development of L-DOPA-induced dyskinesia in a preclinical model of moderate dopamine depletion

Andrew J. Flores, Mitchell J. Bartlett, Blake T. Seaton, Grace Samtani, Morgan R. Sexauer, Nathan C. Weintraub, James R. Siegenthaler, Dong Lu, Michael L. Heien, Frank Porreca, Scott J. Sherman, Torsten Falk

This study shows that blocking kappa opioid receptors increases the rate of L-DOPA-induced dyskinesia development in a rat Parkinson's model but does not affect motor symptoms or tonic dopamine levels.

Brain Research · Dec 1, 2023Peer-reviewedNeuroscience

Heterogeneous neuronal activity in the ventral tegmental area coordinates dopamine release in the nucleus accumbens

Daniel F. Hill, Zachary G. Olson, Mitchell J. Bartlett, Torsten Falk, Michael L. Heien, Stephen L. Cowen

The paper investigates how heterogeneous neuronal activity in the ventral tegmental area coordinates dopamine release in the nucleus accumbens of anesthetized rats.

bioRxiv · Jul 31, 2022 · PreprintNeuroscience