Andrew J. Flores

The paper investigates how levodopa-induced dyskinesia is linked to increased activity in specific striatal direct pathway medium spiny neurons, driven by dopamine and excitatory inputs.

This study identifies how VP GABA and glutamate neurons modulate VTA cell types to drive approach and avoidance behaviors through distinct mechanisms.

This study shows that blocking kappa opioid receptors increases the rate of L-DOPA-induced dyskinesia development in a rat Parkinson's model but does not affect motor symptoms or tonic dopamine levels.