Ewoud Ewing

Systematic comparison of dCas9-based DNA methylation epimodifiers over time indicates efficient on-target and widespread off-target effects

This study compares dCas9-based DNA methylation epimodifiers over time, showing efficient on-target effects but widespread off-target methylation and transcriptional changes.

GeneSetCluster 2.0: a comprehensive toolset for summarizing and integrating gene-sets analysis

GeneSetCluster 2.0 improves gene-set analysis by reducing redundancies, enhancing computational efficiency, and providing accessible tools for both programmers and non-programmers.

Auto-STEED: A data mining tool for automated extraction of experimental parameters and risk of bias items from in vivo publications

Auto-STEED automates extraction of experimental parameters and risk of bias items from in vivo publications, achieving high accuracy and significant time savings.

STATegra: Multi-omics data integration - A conceptual scheme with a bioinformatics pipeline

The paper introduces a conceptual framework and bioinformatics pipeline for multi-omics data integration, validated on TCGA datasets to enhance feature identification compared to single-omics analysis.

Gsta4 controls apoptosis of differentiating adult oligodendrocytes during homeostasis and remyelination via the mitochondria-associated Fas/Casp8/Bid-axis

This study identifies Gsta4 as a regulator of apoptosis in adult oligodendrocyte differentiation and remyelination, showing its role in modulating the Fas/Casp8/Bid mitochondrial axis.