Author

Keiko Akagi

Shandong University of TechnologyORCID 0000-0002-5159-3403Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genomics· 2 Pathology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Approach:statistical model· 2 Assay:whole-genome sequencing· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Research Focus:genome assembly· 1 Organism:human· 1

Frequent Co-Authors

André CorveloiD· 2 shared David E. SymeriD· 2 shared Adel K. El‐NaggariD· 1 shared Amit Agrawal· 1 shared Anne‐Katrin EmdeiD· 1 shared Bee Ling NgiD· 1 shared Beiyuan FuiD· 1 shared Benjamin Hubert· 1 shared

Activity by Year

2022-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersGenomics

André CorveloORCID

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3 papers

Recent·Most cited

A chromosome-level genome assembly of the Hispid cotton rat (Sigmodon hispidus), a model for human pathogenic virus infections

Jingtao Lilue, André Corvelo, Jèssica Gómez‐Garrido, Fengtang Yang, Keiko Akagi, Gia Green, Bee Ling Ng, Beiyuan Fu, Uciel Chorostecki, Sarah Warner, Marina Marcet‐Houben, Thomas Keane, James C. Mullikin, Tyler Alioto, Toni Gabaldón, , Stefan Niewiesk

The paper presents a chromosome-level genome assembly of the Hispid cotton rat, annotating 24,878 protein-coding genes and identifying genetic innovations.

BMC Biology · Jul 18, 2025Peer-reviewedGenomics

SL/Kh Pre-B Lymphomas Originate in the Thymus and are a Model for Primary Mediastinal (Thymic) Large B-Cell Lymphoma

Tami L. Thomae, Si Hui Tan, Keiko Akagi, Jerrold Michael Ward, Neal G. Copeland, Nancy A. Jenkins

This paper identifies thymus-origin pre-B lymphomas in SL/Kh mice and links them to human mediastinal large B-cell lymphoma through Notch1 signaling and retroviral mutagenesis.

bioRxiv · Dec 16, 2024 · PreprintPathology

Diverse tumorigenic consequences of human papillomavirus integration in primary oropharyngeal cancers

David E. Symer, Keiko Akagi, Heather M. Geiger, Song Tao Yang, Gaiyun Li, Anne‐Katrin Emde, Weihong Xiao, Bo Jiang, André Corvelo, Nora C. Toussaint, Jingfeng Li, Amit Agrawal, Enver K. Ozer, Adel K. El‐Naggar, Zoe Du, , Maura L. Gillison

This study identifies HPV integration hotspots in oropharyngeal cancers and shows their role in disrupting host gene expression and genomic stability.

Genome Research · Jan 1, 2022Peer-reviewedGenomics