Suzanne Paradis

This study uses Sema4D to induce inhibitory synapse formation and shows coordinated pre- and postsynaptic protein dynamics during synapse assembly.

This study shows that neuronal activity is essential for the development of touch receptors, as genetic disruption of Piezo2 and Nav1.6 leads to structural and functional defects in mechanosensory neurons.

This study shows that Rem2 inhibits CaMKII activity at synapses, thereby restricting long-term potentiation in the hippocampus.

This study identifies non-redundant roles of Plexin-B1 and Plexin-B2 in GABAergic synapse formation through structure-function analysis and presynaptic expression studies.

This study shows that Sema4D treatment reduces seizure susceptibility and restores benzodiazepine sensitivity in a mouse model of Status Epilepticus.

The paper quantifies how visual experience affects dendritic arbor development in mouse visual cortex, finding limited impact and identifying Rem2 as a regulator.

This study identifies CREB signaling as a pathway inhibited by TDP-43 dysfunction, leading to reduced dendritic complexity in neurodegenerative diseases.

The paper shows that Hebbian learning during network reactivations stabilizes neural representations despite synapse turnover in models of hippocampal and visual cortex circuits.

This study shows Rem2 is essential for ocular dominance plasticity and regulates synaptic scaling and intrinsic excitability in cortical neurons.