Dimeric R25CPTH(1-34) Activates the Parathyroid Hormone-1 Receptor in vitro and Stimulates Bone Formation in Osteoporotic Female Mice
Minsoo Noh, Xiangguo Che, Xian Jin, Dong-Kyo Lee, Hyun‐Ju Kim, Doo Ri Park, Soo Young Lee, Hunsang Lee, Thomas James Gardella, Je‐Yong Choi, Sihoon Lee
This study shows that the dimeric PTH variant R25CPTH(1-34) activates the PTH1R and improves bone formation in osteoporotic mice.
eLife · Mar 28, 2025Peer-reviewedGenomics