Author

Xiangguo Che

Kyungpook National UniversityORCID 0000-0002-7272-1806Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1 Genomics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 2 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Organism:rat· 1

Frequent Co-Authors

Je‐Yong ChoiiD· 3 shared Dong-Kyo LeeiD· 2 shared Hyun‐Ju KimiD· 2 shared Sihoon LeeiD· 2 shared Xian JiniD· 2 shared Dae Won KimiD· 1 shared Doo Ri Park· 1 shared Hunsang LeeiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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3 shared papersMolecular Biology

Je‐Yong ChoiORCID

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3 papers

Recent·Most cited

4-Hexylresorcinol Enhances Skeletal Muscle Glucose Handling through the AMPK-GLUT4 axis in Diabetic Rats

Xiangguo Che, Seung-Ki Hong, Ji-Hyeon Oh, S. K. PARK, Jongho Choi, Suk Keun Lee, Dae Won Kim, You‐Young Jo, Seong‐Gon Kim, Je‐Yong Choi

This study shows that 4-hexylresorcinol improves glucose metabolism in diabetic rats by enhancing AMPK-GLUT4 signaling and glycogen content.

bioRxiv · Jan 20, 2026 · PreprintMolecular Biology

Dimeric R25CPTH(1-34) Activates the Parathyroid Hormone-1 Receptor in vitro and Stimulates Bone Formation in Osteoporotic Female Mice

Minsoo Noh, Xiangguo Che, Xian Jin, Dong-Kyo Lee, Hyun‐Ju Kim, Doo Ri Park, Soo Young Lee, Hunsang Lee, Thomas James Gardella, Je‐Yong Choi, Sihoon Lee

This study shows that the dimeric PTH variant R25CPTH(1-34) activates the PTH1R and improves bone formation in osteoporotic mice.

eLife · Mar 28, 2025Peer-reviewedGenomics

Phospholipase C β4 promotes RANKL-dependent osteoclastogenesis by interacting with MKK3 and p38 MAPK

Dong-Kyo Lee, Xian Jin, Poo-Reum Choi, Ying Jun Cui, Xiangguo Che, Sihoon Lee, Keun Hur, Hyun‐Ju Kim, Je‐Yong Choi

This study identifies PLCβ4 as a key regulator of RANKL-induced osteoclastogenesis by interacting with MKK3 and p38 MAPK, showing its potential as a therapeutic target for bone diseases.

Experimental & Molecular Medicine · Feb 2, 2025Peer-reviewedCell Biology