Author

Thomas James Gardella

Harvard UniversityORCID 0000-0002-2163-5772Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Genomics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Organism:mouse· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Alissa J. NelsoniD· 1 shared Caroline Houghton· 1 shared Dong-Kyo LeeiD· 1 shared Doo Ri Park· 1 shared Garyfallia PapaioannouiD· 1 shared Hunsang LeeiD· 1 shared Hyun‐Ju KimiD· 1 shared Je‐Yong ChoiiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperMolecular Biology

Alissa J. NelsonORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Dimeric R25CPTH(1-34) Activates the Parathyroid Hormone-1 Receptor in vitro and Stimulates Bone Formation in Osteoporotic Female Mice

Minsoo Noh, Xiangguo Che, Xian Jin, Dong-Kyo Lee, Hyun‐Ju Kim, Doo Ri Park, Soo Young Lee, Hunsang Lee, Thomas James Gardella, Je‐Yong Choi, Sihoon Lee

This study shows that the dimeric PTH variant R25CPTH(1-34) activates the PTH1R and improves bone formation in osteoporotic mice.

eLife · Mar 28, 2025Peer-reviewedGenomics

Regulation of intracellular cAMP levels in osteocytes by mechano-sensitive focal adhesion kinase via PDE8A

Garyfallia Papaioannou, Tadatoshi Sato, Caroline Houghton, Parthena E. Kotsalidis, Katelyn Strauss, Thomas Dean, Alissa J. Nelson, Matthew P. Stokes, Thomas James Gardella, Marc Nathan Wein

This study identifies FAK's role in regulating cAMP levels in osteocytes through PDE8A, showing FAK inhibition increases cAMP and downstream signaling.

bioRxiv · Jun 28, 2024 · PreprintMolecular Biology